AMC Respiratory - Detection of Respiratory Infections

Description

Detection of Respiratory System Infections

AMC Respiratory is a clinical analysis to detect potential infections in the respiratory system. The analysis detects all microorganisms present in the blood sample, enabling the identification of all pathogenic microorganisms.

Complete Viral Detection

Detects all microorganisms present in the blood sample including respiratory viruses and other pathogens.

Respiratory System

Specialized analysis to detect infections and infestations affecting the respiratory system.

Microorganisms Detected

Bacteria

• Streptococcus pneumoniae
• Haemophilus influenzae
• Staphylococcus aureus
• Pseudomonas aeruginosa
• Mycoplasma pneumoniae
• Legionella spp.

Advantages of the Analysis

• Detects all microorganisms present
• Blood sample analysis
• Identifies infections and infestations
• Crucial early detection
• Prevents undesirable consequences
• High-precision technology

Technology

Nanopore NGS Respiratory Technology

We apply Nanopore NGS technology optimized for respiratory samples, providing high sensitivity to detect pathogens in samples with low microbial load and simultaneous analysis of multiple types of microorganisms.

Optimization for Respiratory Samples

High Sensitivity

• ✅ Detection in low-load samples
• ✅ Identification of coinfections
• ✅ Accurate quantitative analysis
• ✅ Detection of atypical pathogens

Comprehensive Analysis

• ✅ Bacteria, viruses and fungi simultaneously
• ✅ Pathogen-specific resistances
• ✅ Virulence factors
• ✅ Severity biomarkers

Sample

Respiratory Sample Types

Accepted Samples

Nasopharyngeal swab

Gold standard sample for upper tract pathogens

Sputum

Ideal for lower respiratory tract pathogens

Bronchoalveolar lavage

Maximum sensitivity in critically ill patients

Optimal Collection

Collection protocol:

• Early collection in the course of the disease
• Use of swabs with viral transport medium
• Storage at 4°C during transport
• Processing within 48 hours maximum
• Avoid contamination with saliva

Sample Quality

The quality and timing of collection are crucial to obtain accurate results in acute respiratory infections.

Results

Complete Respiratory Report

The AMC Respiratory report provides accurate identification of respiratory pathogens, quantification of microbial loads and detailed analysis of antimicrobial resistances to guide optimal treatment.

Pathogen Identification

• Qualitative and quantitative detection
• Differentiation of colonization vs infection
• Identification of multiple coinfections
• Molecular typing of strains

Resistance Profile

• Resistance to β-lactam antibiotics
• Resistance to macrolides and quinolones
• Antiviral resistance (oseltamivir, etc.)
• Targeted therapeutic recommendations

Turnaround Time: 15 business days

Specialized report that includes:

• Complete panel of respiratory pathogens
• Quantification of microbial loads
• Antimicrobial resistance map
• Specific treatment recommendations
• Clinical follow-up protocol

Clinical indications

AMC Respiratory is indicated to detect infections and infestations of the respiratory system that have significant health implications.

Specific Indications

• Lung cancer
• Respiratory tract infections
• Pulmonary nodule
• Tuberculosis (suspected)
• Respiratory viral infections
• Other respiratory pathologies

Target Microorganisms

• Respiratory viruses (Coronavirus, RSV)
• Adenovirus and Parainfluenza
• Human Metapneumovirus
• Exacerbated COPD
• Cystic fibrosis
• ICU and critical care

High-Priority Cases

Especially recommended in severe respiratory infections, empirical treatment failures and suspicion of multidrug-resistant pathogens.